TB500 (Thymosin Beta-4 acetate) 5mg is a widely studied actin-sequestering peptide supplied as lyophilized powder for foundational research into cytoskeletal dynamics and tissue regeneration signaling pathways in preclinical models.

Compound Information:

• Chemical Name: Thymosin Beta-4 Acetate
• Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
• Molecular Weight: 4963.5 Da
• Compound Class: Actin-binding peptide; thymosin family

TB500 functions primarily through interaction with monomeric G-actin, promoting actin polymerization and regulating intracellular cytoskeletal organization. This mechanism underlies its extensive use in preclinical studies examining cellular migration, vascular network formation, and extracellular matrix remodeling.

Research Applications:

• In-vitro assessment of actin polymerization kinetics and G-actin sequestration dynamics in fibroblast cultures
• Evaluation of endothelial cell migration rates and tubulogenesis in angiogenesis scratch-wound assays
• Analysis of cytoskeletal reorganization patterns during cellular differentiation protocols
• Investigation of Thymosin Beta-4 interaction with PINCH-ILK-parvin complex signaling in adhesion models
• Characterization of extracellular matrix metalloproteinase modulation in collagen gel invasion assays

Storage and Handling:

• Store lyophilized powder at -20°C in sealed vials protected from light
• Reconstitute with sterile bacteriostatic water prior to use
• Avoid multiple freeze-thaw cycles to preserve bioactivity
• Reconstituted solution stable for up to 21 days at 2-8°C

Product Specifications:

• Purity: ≥98% (HPLC)
• Appearance: White lyophilized powder
• Form: Lyophilized powder
• Quantity: 5mg per vial

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.