GLP-2 Receptor Agonist Analog (TRZ designation) is available as lyophilized powder in 5mg vials for preclinical gastrointestinal physiology and intestinal growth factor research. This synthetic GLP-2 receptor agonist investigates incretin signaling in enterocyte health and nutrient absorption pathways.

Chemical Composition:

• Chemical Name: GLP-2 Receptor Agonist Analog
• Molecular Formula: C185H291N51O59S6 (representative structure)
• Molecular Weight: ~3,981 g/mol (approximate)
• Compound Class: GLP-2 receptor agonist; intestinotrophic hormone analog

This GLP-2 receptor agonist analog represents a research-grade formulation designed to activate GLP-2 receptor signaling with enhanced receptor selectivity and stability. The 5mg dosage supports baseline characterization of intestinal effects and receptor engagement studies. Research applications encompass evaluation of enterocyte proliferation and intestinal epithelial growth in organ culture systems, investigation of nutrient transporter expression (glucose, amino acid transporters) in intestinal tissue, assessment of tight junction protein expression and barrier function integrity, and assessment of blood flow regulation in mesenteric vasculature supporting nutrient absorption.

Research Applications:

• Enterocyte proliferation assessment via BrdU incorporation in intestinal crypts
• Intestinal epithelial growth factor expression profiling (EGF, FGF, VEGF)
• Tight junction protein characterization (zonula occludens-1, occludin, claudins)
• Nutrient transporter expression evaluation (SGLT1, GLUT2, PepT1)
• Mucosal blood flow assessment using laser doppler perfusion imaging

Storage and Handling:

• Store lyophilized powder at -20°C in sealed, light-protected vials
• Maintain desiccated conditions; prevent moisture and humidity exposure
• Reconstitute with sterile, endotoxin-free water for injection
• Solution stability: 7 days at 4°C once reconstituted

Product Specifications:

• Form: Lyophilized powder
• Quantity: 5mg per vial
• Purity: >95% by HPLC
• Appearance: White lyophilized cake

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.