MOTS-C at 12mg dosage represents a higher-concentration formulation of the mitochondrial-derived peptide, optimized for large-scale preclinical investigations. Supplied as lyophilized powder, this formulation enables comprehensive cellular energy metabolism studies and extended research protocols examining mitochondrial stress responses and adaptive signaling pathways.

Chemical/Compound Information:

• Chemical Name: MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA-C)
• Molecular Formula: C69H108N18O17
• Molecular Weight: 1457.71 g/mol
• Compound Class: Mitochondrial-Derived Signaling Peptide

The 12mg concentration provides increased flexibility for dose-ranging studies and supports investigation of MOTS-C effects across multiple biological systems. This format facilitates simultaneous multi-endpoint assay development and permits comprehensive characterization of mitochondrial stress response kinetics.

Research Applications:

• Dose-dependent AMPK activation profiling across physiologically relevant concentration ranges
• Cellular energy metabolism under diverse nutrient and oxygen conditions
• Mitochondrial stress tolerance assessment in aged vs. young cell preparations
• Metabolic flexibility and substrate preference switching following MOTS-C exposure
• Integration of MOTS-C signaling with other metabolic regulators (NAD+, PGC-1α)

Storage and Handling:

• Store at -20°C in sealed vial with desiccant in low-light environment
• Avoid repeated freeze-thaw events; prepare single-use aliquots for each experiment
• Reconstitute in sterile PBS, saline, or culture medium per protocol specifications
• Maintain sterile technique throughout handling and reconstitution
• Prepare working concentrations immediately before experimental application

Product Specifications:

• Purity: ≥96% (HPLC/MS)
• Appearance: White to off-white lyophilized powder
• Form: Lyophilized powder
• Quantity: 12mg per vial

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.