Tesofensine is a selective triple monoamine reuptake inhibitor targeting serotonin, norepinephrine, and dopamine transporters, investigated in preclinical research examining monoaminergic neurotransmission and appetite regulation. This 500 mcg tablet formulation is optimized for in-vitro transporter studies and ex-vivo neurotransmitter dynamics research. The 100-tablet format supports systematic dose-response investigations of monoamine reuptake inhibition.

Chemical Specifications:

• Chemical Name: 1-(4-methylphenyl)-N,N-diethyl-1-phenyl-methanamine (approximate structure)
• Molecular Formula: C18H23N
• Molecular Weight: 253.38 g/mol
• Compound Class: Triple monoamine reuptake inhibitor

Tesofensine functions as a selective inhibitor of serotonin (SERT), norepinephrine (NET), and dopamine (DAT) reuptake transporters, enabling preclinical investigations of monoaminergic signaling. Research applications focus on transporter pharmacology, monoamine dynamics, and neurotransmitter pathway characterization in laboratory models.

Research Applications:

• Characterizing serotonin, norepinephrine, and dopamine transporter inhibition kinetics
• Investigating monoamine accumulation in synaptic compartments and neural tissue
• Modeling neurotransmitter signaling changes in cell-based reuptake assays
• Examining monoaminergic pathway regulation in ex-vivo neural preparations
• Evaluating transporter selectivity and potency across all three monoamine systems

Storage and Handling:

• Store at room temperature (20-25°C) in light-resistant, sealed containers
• Keep tablets in original packaging with desiccant protection
• Maintain controlled humidity and stable storage temperature
• Protect from moisture and direct sunlight exposure

Product Specifications:

• Purity: >98% HPLC
• Form: Tablets, 500 mcg each
• Appearance: White to off-white tablets with uniform appearance
• Quantity: 100 tablets (50 mg total)

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.