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Melatonin is an indoleamine neurohormone synthesized by the pineal gland and distributed throughout the body. Supplied as lyophilized powder, Melatonin is extensively utilized in chronobiology research, circadian rhythm investigation, and studies of melatonin receptor signaling in mammalian physiology models.
Chemical/Compound Information:
• Chemical Name: N-Acetyl-5-methoxytryptamine
• Molecular Formula: C13H16N2O2
• Molecular Weight: 232.28 g/mol
• Compound Class: Indoleamine Neurohormone
Melatonin serves as the primary synchronizing signal for circadian rhythm regulation through MT1 and MT2 receptor activation. Its application in research permits detailed examination of temporal biology, sleep-wake cycle signaling, and circadian-regulated metabolic processes in controlled laboratory systems.
Research Applications:
• Circadian rhythm synchronization and period adjustment in cell culture and tissue models
• MT1/MT2 melatonin receptor binding kinetics and subtype selectivity assessment
• Pineal gland function and melatonin synthesis pathway investigation
• Circadian-regulated gene expression timing and phase-shift characterization
• Antioxidant mechanisms and radical scavenging activities in isolated tissue preparations
Storage and Handling:
• Store at -20°C in sealed light-protected amber vial
• Maintain low-humidity environment; include desiccant in storage container
• Reconstitute in sterile water or appropriate buffer immediately before use
• Protect from light exposure during all handling steps
• Single-use aliquots recommended to prevent degradation
Product Specifications:
• Purity: ≥99% (HPLC)
• Appearance: White to off-white lyophilized powder
• Form: Lyophilized powder
• Quantity: 10mg per vial
FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.