Melanotan 2 Acetate is a non-selective melanocortin receptor agonist with broad affinity across MC1R, MC3R, MC4R, and MC5R subtypes. Supplied as lyophilized powder, MT-2 serves as a crucial research tool for comparative melanocortin receptor subtype pharmacology and investigation of polyvalent GPCR signaling in complex cellular systems.

Chemical/Compound Information:

• Chemical Name: Melanotan II acetate salt
• Molecular Formula: C50H69N15O8S
• Molecular Weight: 1084.24 g/mol
• Compound Class: Non-selective Melanocortin Receptor Agonist

MT-2’s broad receptor subtype affinity enables systematic examination of pleiotropic melanocortin signaling across multiple receptor isoforms. This property makes MT-2 invaluable for studies contrasting MC-receptor-dependent vs. independent mechanisms and for investigating receptor cross-talk in cells co-expressing multiple MC subtypes.

Research Applications:

• Melanocortin receptor subtype selectivity profiling across MC1R, MC3R, MC4R, MC5R
• Polyvalent GPCR signaling and desensitization kinetics in multi-receptor cell systems
• cAMP accumulation assays comparing single vs. dual/triple receptor activation
• Functional selectivity and biased signaling characterization across MC receptor subtypes
• Comparative SAR analysis: MT-1 (selective) vs. MT-2 (non-selective) binding patterns

Storage and Handling:

• Store at -20°C in sealed, light-protected vial
• Include desiccant; maintain dry environment throughout storage
• Reconstitute in sterile PBS or assay buffer; prepare fresh immediately before use
• Avoid light exposure during all handling steps to prevent photodegradation
• Single-use aliquoting recommended to maintain biological activity

Product Specifications:

• Purity: ≥96% (HPLC/MS)
• Appearance: White to off-white lyophilized powder
• Form: Lyophilized powder
• Quantity: 10mg per vial

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.