Semax is a synthetic heptapeptide analog of ACTH 4-10, characterized as a cognition-enhancing neuropeptide. Supplied as lyophilized powder, Semax is utilized in preclinical neuroscience research investigating brain-derived neurotrophic factor (BDNF) signaling, neurotrophin pathways, and neuropeptide-mediated cognitive enhancement mechanisms in neural tissue models.

Chemical/Compound Information:

• Chemical Name: Semax (ACTH 4-10 analog)
• Molecular Formula: C35H50N8O8
• Molecular Weight: 718.82 g/mol
• Compound Class: Synthetic Neuropeptide / Cognition Enhancer

Semax exhibits cognitive-enhancing properties through ACTH receptor-independent mechanisms involving BDNF pathway activation. Its investigation enables systematic examination of neuropeptide-derived cognition enhancement and characterization of BDNF-dependent neuroplasticity in learning and memory research.

Research Applications:

• Brain-derived neurotrophic factor (BDNF) expression and mRNA transcript quantification
• TrkB neurotrophin receptor signaling and MAPK/PI3K cascade activation kinetics
• Memory formation and consolidation enhancement in behavioral learning paradigms
• Neuroprotection mechanisms: oxidative stress resistance in neural tissue models
• Comparative neurotrophin signaling: Semax vs. direct BDNF administration outcomes

Storage and Handling:

• Store at -20°C in sealed vial protected from light exposure
• Minimize freeze-thaw cycles; prepare single-use aliquots immediately upon receipt
• Reconstitute in sterile PBS or appropriate neural tissue culture medium
• Maintain inert (N2) atmosphere in storage vials to prevent peptide oxidation
• Use reconstituted solutions within 4 hours to preserve neuroprotective bioactivity

Product Specifications:

• Purity: ≥95% (HPLC)
• Appearance: White to off-white lyophilized powder
• Form: Lyophilized powder
• Quantity: 5mg per vial

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.