Tadalafil is a selective phosphodiesterase-5 inhibitor utilized in preclinical research investigating vascular smooth muscle signaling and PDE-5-mediated pathways in multiple tissue models. This PharmaQO-sourced 20 mg tablet formulation is optimized for comprehensive in-vitro and ex-vivo research examining cGMP dynamics, vascular endothelial function, and phosphodiesterase enzyme kinetics. The 50-tablet format supports systematic dose-response investigations in laboratory settings examining vascular physiology and endothelial function mechanisms.

Chemical Specifications:

• Chemical Name: (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,12,12a-pentahydro-2-methyl-pyrido[1′,2′:4,5]pyrimido[1,2-b][1,3]benzodiazepin-1(4H)-one
• Molecular Formula: C22H19N3O4
• Molecular Weight: 389.41 g/mol
• Compound Class: Phosphodiesterase-5 inhibitor

Tadalafil functions as a selective PDE-5 inhibitor with extended half-life characteristics, enabling research into sustained cGMP signaling in vascular tissue models. The compound supports investigations of vascular smooth muscle relaxation mechanisms and endothelial function in controlled preclinical protocols.

Research Applications:

• Examining phosphodiesterase-5 inhibition kinetics in enzyme assays
• Investigating cGMP signaling dynamics in vascular smooth muscle cell cultures
• Modeling sustained PDE-5 inhibition in vascular tissue preparations
• Characterizing dose-dependent vascular reactivity in isolated vessel studies
• Evaluating endothelial function and nitric oxide signaling pathways

Storage and Handling:

• Store at room temperature (20-25°C) in light-resistant containers
• Keep tablets in original packaging with desiccant to control moisture
• Maintain stable storage temperature away from extreme heat
• Protect from humidity and direct sunlight exposure

Product Specifications:

• Purity: >98% HPLC
• Form: Tablets, 20 mg each
• Appearance: Yellow to golden-yellow tablets with film coating
• Quantity: 50 tablets (1000 mg total)

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.