SLU-PP-332 + BAM15 combination compound pairs the ERRα/ERRγ agonist SLU-PP-332 with the selective mitochondrial uncoupler BAM15, creating a dual-mechanism research tool for investigating coordinated mitochondrial pathway modulation. Supplied as lyophilized powder at 300mcg total.

Compound Information:

• Components: SLU-PP-332 (ERRα/ERRγ agonist) + BAM15 (mitochondrial protonophore)
• Target Pathways: ERR-mediated transcription + mitochondrial proton gradient uncoupling
• Molecular Class: Dual small-molecule combination (nuclear receptor agonist + mitochondrial uncoupler)
• Purity: ≥98% each component

This combination enables simultaneous activation of ERR-dependent mitochondrial biogenesis programs alongside direct mitochondrial membrane potential modulation via BAM15, allowing researchers to study synergistic versus additive effects on cellular energy expenditure pathways.

Research Applications:

• Synergy assessment between ERR-driven transcriptional upregulation and direct mitochondrial uncoupling in cellular respiration assays
• Comparative analysis of dual-mechanism metabolic effects versus individual compound administration in adipocyte models
• Evaluation of combined mitochondrial biogenesis stimulation and proton leak effects on oxygen consumption rates
• Investigation of BAM15-mediated uncoupling efficiency in the context of ERR-enhanced mitochondrial density
• Assessment of cellular ATP/ADP ratios under coordinated nuclear receptor activation and membrane potential dissipation

Storage and Handling:

• Store sealed at -20°C protected from light and moisture
• Reconstitute with appropriate solvent immediately prior to experimental use
• Avoid repeated freeze-thaw cycles
• Use within 14 days of reconstitution when stored at 2-8°C

Product Specifications:

• Purity: ≥98% (each component)
• Appearance: White to off-white lyophilized powder
• Form: Lyophilized combination powder
• Quantity: 300mcg total per vial

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.