Prednisone
$60.00
Prednisone Qty is 100 at 1000mg (10mg) each.
- Research grade
- USA made
Out of stock
- Certificate of analysis available per batch
- Ships from a US facility
- Free shipping on orders over $175
- COA available Certificate of analysis per batch
- USA made Third-party verified
- Same-day dispatch On orders placed before cut-off
- Free shipping over $175 Applied automatically at checkout
About Prednisone
Prednisone is a synthetic corticosteroid functioning as a glucocorticoid receptor agonist. Supplied as lyophilized powder, Prednisone is utilized in preclinical research examining glucocorticoid receptor signaling, immunosuppressive mechanisms, and steroid hormone pharmacology in cellular and tissue models investigating inflammation and immune function.
Chemical/Compound Information:
- Chemical Name: 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
- Molecular Formula: C21H26O5
- Molecular Weight: 358.43 g/mol
- Compound Class: Synthetic Corticosteroid / Glucocorticoid Receptor Agonist
Prednisone serves as a prodrug activated by hepatic 11β-hydroxysteroid dehydrogenase to form the active metabolite prednisolone. Investigation of prednisone enables systematic exploration of glucocorticoid receptor-mediated gene transcription, anti-inflammatory signaling cascades, and steroid hormone pharmacodynamics in preclinical immunology models.
Research Applications:
- Glucocorticoid receptor (GR) ligand-binding domain interactions and transactivation kinetics
- GR-mediated inflammatory gene suppression in TNF-α or LPS-stimulated cell models
- Immune cell differentiation effects: T regulatory cell induction vs. effector T cell suppression
- Glucocorticoid-induced apoptosis and cell cycle arrest in lymphocyte populations
- Dose-dependent GR occupancy and transcriptional response characterization
Storage and Handling:
- Store at 2-8°C in sealed vial protected from light exposure
- Minimize humidity; include desiccant in storage container
- Reconstitute in DMSO or ethanol for cell-based assays; use PBS for biochemical assays
- Prepare working solutions immediately before experiments
- Protect from direct sunlight throughout all handling steps
Product Specifications:
- Purity: ≥99% (HPLC)
- Appearance: White to off-white lyophilized powder
- Form: Lyophilized powder
- Quantity: As specified per vial labeling
FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.
Technical data
- Chemical Name
- 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
- Molecular Formula
- C21H26O5
- Molecular Weight
- 358.43 g/mol
- Compound Class
- Synthetic Corticosteroid / Glucocorticoid Receptor Agonist
Frequently asked questions
What is Prednisone?
Prednisone is supplied for laboratory research as a Synthetic Corticosteroid / Glucocorticoid Receptor Agonist. Full background, mechanism and research context are set out in the description above.
What is the molecular formula and weight of Prednisone?
Molecular formula C21H26O5, molecular weight 358.43 g/mol.
How is Prednisone supplied?
In tablet form. The quantity and strength for this listing are given in the product name above.
Can Prednisone be used in humans or animals?
No. Every compound on this site is supplied for laboratory and research use only, and is not for human or veterinary use or consumption.
Research use only
Prednisone is supplied strictly as a research chemical for laboratory use. It is not for human or veterinary use or consumption, is not a drug, food or supplement, and is not approved by the U.S. Food and Drug Administration for any purpose.
Handle only in a controlled laboratory setting, by qualified personnel, in accordance with applicable law and good laboratory practice.