GLP-2 Receptor Agonist Analog (TRZ designation) is available as lyophilized powder in 15mg vials, enabling extensive intestinal disease model research and tissue regeneration investigations. This dosage supports multi-institutional collaborative studies of gastrointestinal physiology.

Chemical Composition:

• Chemical Name: GLP-2 Receptor Agonist Analog
• Molecular Formula: C185H291N51O59S6 (representative structure)
• Molecular Weight: ~3,981 g/mol (approximate)
• Compound Class: GLP-2 receptor agonist; intestinotrophic hormone analog

The 15mg formulation facilitates investigation of GLP-2 effects in complex disease models including inflammatory bowel disease (IBD) contexts, short bowel syndrome adaptation, and chemotherapy-induced intestinal injury recovery protocols. Research encompasses evaluation of GLP-2-mediated anti-inflammatory signaling suppressing pro-inflammatory cytokine production (TNF-α, IL-6), investigation of intestinal stem cell differentiation and epithelial regeneration in injury recovery models, assessment of microbial dysbiosis correction and microbiome composition changes, and characterization of nutrient malabsorption restoration in disease-compromised intestinal epithelium.

Research Applications:

• Pro-inflammatory cytokine profiling (TNF-α, IL-1β, IL-6) in intestinal tissue
• Intestinal stem cell and progenitor cell activation assessment via immunostaining
• Microbiome composition analysis via 16S rRNA sequencing post-GLP-2 treatment
• Calcium and amino acid absorption efficiency evaluation in disease models
• Intestinal barrier integrity restoration assessment using trans-epithelial electrical resistance

Storage and Handling:

• Store lyophilized powder at -20°C in sealed, light-protected containers
• Maintain in dry storage conditions with desiccant protection
• Prepare fresh reconstitutions for each experimental series
• Reconstituted solutions stable at 4°C for 7 days; prepare aliquots as needed

Product Specifications:

• Form: Lyophilized powder
• Quantity: 15mg per vial
• Purity: >95% by HPLC
• Appearance: White lyophilized powder

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.