GLP-2 Receptor Agonist Analog (TRZ designation) is supplied as lyophilized powder in 40mg vials, providing extended research capacity for comprehensive intestinal physiology investigation and preclinical disease model assessment. This larger dosage supports intensive mechanistic characterization protocols.

Chemical Composition:

• Chemical Name: GLP-2 Receptor Agonist Analog
• Molecular Formula: C185H291N51O59S6 (representative structure)
• Molecular Weight: ~3,981 g/mol (approximate)
• Compound Class: GLP-2 receptor agonist; intestinotrophic hormone analog

The 40mg vial format facilitates parallel experimental arms with multiple timepoint sampling, investigation of GLP-2 effects on enteric nervous system development and neuronal plasticity in intestinal tissue, assessment of intestinal-derived hormone and neuropeptide production changes secondary to GLP-2 receptor activation, and characterization of systemic endocrine effects mediated through intestinal nutrient sensing pathways. Research encompasses mechanistic evaluation of GLP-2-dependent changes in gut-derived regulatory peptides (PYY, neurotensin, substance P), investigation of enteric neuron phenotype and neurotransmitter expression alterations, assessment of intestinal permeability-related systemic endotoxemia changes, and evaluation of GLP-2-mediated systemic immune tolerance mechanisms in intestinal health restoration.

Research Applications:

• Enteric nervous system neuronal phenotyping via immunohistochemistry and electron microscopy
• Gut-derived peptide hormone expression profiling (PYY, neurotensin, VIP, substance P)
• Lipopolysaccharide (LPS) translocation assessment in intestinal barrier dysfunction models
• Systemic endotoxin and inflammatory marker profiling (LPS binding protein, CD14)
• Regulatory T cell (Treg) abundance and function assessment in intestinal tissue

Storage and Handling:

• Store at -20°C in sealed vials protected from light exposure
• Maintain desiccated conditions to preserve peptide stability
• Reconstitute fresh with sterile water for each experimental batch
• Reconstituted solutions remain stable at 4°C for 7 days maximum

Product Specifications:

• Form: Lyophilized powder
• Quantity: 40mg per vial
• Purity: >95% by HPLC
• Appearance: White crystalline lyophilized powder

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.