IGF-DES (Des 1-3 IGF-1) 1mg is a truncated insulin-like growth factor variant supplied for preclinical research investigating IGF receptor signaling specificity. This preparation supports controlled laboratory studies of IGF-1 receptor binding mechanisms and growth factor receptor biology.

Chemical Compound Information:

• Chemical Name: IGF-1 (des 1-3) – truncated insulin-like growth factor
• Molecular Formula: C₅₈H₉₀N₁₆O₁₃S (approximate)
• Molecular Weight: ~7,378 Da
• Compound Class: Peptide growth factor; IGF-1 receptor selective ligand

Description:
IGF-DES is a variant of insulin-like growth factor lacking the first three amino acids. This truncated form exhibits altered receptor binding properties and enables investigation of structure-function relationships in IGF signaling. The 1mg formulation supports systematic study of IGF receptor specificity.

Research Applications:

• Investigation of des(1-3) IGF-1 receptor binding selectivity and affinity parameters
• Study of IGF-1 receptor tyrosine kinase pathway activation in cell systems
• Evaluation of differential signaling between IGF-1 receptor and insulin receptor
• Assessment of growth factor effects on skeletal muscle protein synthesis
• Examination of IGF variant effects on cell survival and proliferation pathways

Storage and Handling:

• Store lyophilized powder at -20°C in sealed, light-protected vials
• Prepare solutions in sterile water or appropriate growth factor diluents
• Maintain working solutions at 2-8°C; use within 48 hours
• Handle with sterile technique to prevent contamination and degradation

Product Specifications:

• Purity: >95% by HPLC analysis
• Form: Lyophilized powder
• Quantity: 1mg per vial
• Appearance: White to off-white fine powder

FOR RESEARCH USE ONLY. Not intended for human consumption or clinical use. All products are sold strictly for laboratory, educational, and scientific research purposes.